Acamprosate Dosing

Your healthcare provider will take several factors into account when calculating your dose of acamprosate, including how well your kidneys are functioning and how you respond to the drug. In most cases, the dosage for treating alcohol dependence is two 333-mg tablets taken three times a day. If you have kidney problems, you may need a lower amount.

An Introduction to Your Dose of Acamprosate

The dose of acamprosate calcium (Campral®) your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • How well your kidneys are functioning
  • How you respond to acamprosate.
     
As is always the case, do not adjust your dose unless your healthcare provider specifically tells you to do so.
 

Acamprosate Dosage for Alcohol Dependence

The recommended dose of acamprosate for most people is 666 mg (taken as two 333-mg tablets) three times daily, although a lower dosage may be effective in some people. Ideally, the drug should be started as soon as possible after alcohol is stopped. It is not approved for use in people who have not yet stopped drinking.
 
Acamprosate is not meant to be used alone; it should be used with an appropriate treatment program, including counseling and group sessions as necessary.
 
Because the kidneys help remove acamprosate from the body, people who have kidney problems may not be able to adequately remove the drug from the body as well as they should. For people with moderate kidney problems, the recommended dose is acamprosate 333 mg three times daily. For people with severe kidney problems, the drug is not recommended.
 

General Information on Taking Acamprosate

Considerations to keep in mind during treatment with acamprosate include the following:
 
  • The medication comes in the form of a delayed-release tablet. It is taken by mouth, usually three times a day.
     
  • You can take an acamprosate dosage with or without food. If the medication bothers your stomach, try taking it with a little food. It may be helpful to take acamprosate with meals so that you remember to take it.
     
  • Do not break, cut, or chew the tablets, as this will destroy the delayed-release coating on them.
     
  • Make sure to take acamprosate at the same times each day to maintain an even level in your blood.
     
  • It can take up to five days for an effective and steady level of acamprosate to accumulate in the body. Don't give up too early.
     
  • If you have a relapse and start drinking again, do not stop taking acamprosate unless your healthcare provider instructs you to do so.
     
  • For the medication to work properly, it must be taken as prescribed. Acamprosate will not work if you stop taking it.
     
  • If you are unsure about anything related to dosing with acamprosate, talk with your doctor, nurse, or pharmacist. Do not stop taking the drug without first discussing it with your healthcare provider.
     
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Acamprosate Calcium Drug Info

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