Drug Interactions With Avanafil

More Information on Drug Interactions With Avanafil

The following sections explain in detail the potentially negative reactions that can occur when avanafil is combined with any of the drugs listed above.
 
Alcohol
You should not consume more than three alcoholic drinks while taking avanafil, such as three glasses of wine or beer, or three shots of liquor. Doing so could cause problems, such as:
 
  • An increase in heart rate
  • A decrease in blood pressure (especially upon standing)
  • Dizziness
  • Lightheadedness
  • Headache.
     
Alpha Blockers
Combining avanafil with an alpha blocker can cause low blood pressure (hypotension). If your blood pressure gets too low, you might become dizzy, lightheaded, or faint. If you are taking an alpha blocker, you will be started on a lower avanafil dosage.
 
Blood Pressure Medications
If you take avanafil in combination with a blood pressure-lowering medicine, your blood pressure may become too low. If this happens, you might become dizzy, lightheaded, or faint. If you are taking blood pressure medicines, you may need a lower avanafil dosage.
 
CYP 3A4 Inducer Medications
The liver breaks down avanafil using enzymes known as CYP 3A4 enzymes. Certain medications known as CYP 3A4 inducers can increase the activity of these enzymes. Combining avanafil with one of these CYP 3A4 inducers may decrease the level of avanafil in your bloodstream, making it less effective. The manufacturer of avanafil recommends that this drug should not be taken with a CYP 3A4 inducer.
 
CYP 3A4 Inhibitor Medications
The liver breaks down avanafil using enzymes known as CYP 3A4 enzymes. Certain medications known as CYP 3A4 inhibitors can decrease the activity of these enzymes. Combining avanafil with one of these CYP 3A4 inhibitors may increase the level of avanafil in your bloodstream, increasing your risk for serious side effects.
 
The maximum recommended avanafil dose in people using moderate CYP 3A4 inhibitors is avanafil 50 mg, no more often than once a day. People taking strong CYP 3A4 inhibitors should not use avanafil. Your healthcare provider will know which CYP 3A4 inhibitors are strong inhibitors and which are moderate inhibitors.
Men and Osteoporosis

Avanafil Medication Information

Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2017 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.