Drug Interactions With Dutasteride

There are many potential drug interactions with dutasteride to be aware of. Taking dutasteride with some other drugs -- such as nefazodone, clarithromycin, telithromycin, or certain antifungal medications -- can increase the level of dutasteride in your blood, potentially increasing your risk of side effects. It is important to talk with your healthcare provider about any drug interactions with dutasteride that may apply to you.

 

Drug Interactions With Dutasteride -- An Overview

Dutasteride (Avodart®) can potentially interact with many drugs. Some of the drugs that may lead to dutasteride interactions include:
 
  • Certain HIV medications, including:
o Ritonavir (Norvir®). 
  • Certain antifungal medications, including:
o Itraconazole (Sporanox®)
o Ketoconazole (Nizoral®)
o Miconazole.
  • Clarithromycin (Biaxin®)
     
  • Conivaptan (Vaprisol®)
     
  • Diclofenac (Voltaren®, Cataflam®)
     
  • Imatinib (Gleevec®)
     
  • Isoniazid (Nydrazid®)
     
  • Nefazodone (Serzone®)
     
  • Nicardipine (Cardene®)
     
  • Propofol (Diprivan®)
     
  • Quinidine
     
  • Telithromycin (Ketek®).
     
(Drug Interactions With Dutasteride Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;