Finasteride

Effectiveness for BPH

There have been several studies looking at how well finasteride treats an enlarged prostate. In particular, there has been one very large study that studied several of the effects of finasteride for men with BPH, with the following results:
 
Symptoms of BPH
The men in this study were asked to rate the following symptoms of BPH:
 
  • Decreased size and force of urine stream
  • Feeling of incomplete bladder emptying when urinating
  • Delayed or interrupted urination
  • Having to get up to urinate frequently during the night
  • Having to urinate frequently during the day
  • Needing to strain or push the flow of urine.
     
The men who took finasteride had significant improvement in their BPH symptoms compared to the men who did not take finasteride. While some patients saw improvement right away, in general, it took about six months to see the improvement for most men. This improvement lasted throughout the entire study period (four years).
 
Acute Urinary Retention
This study also looked at how many men had acute urinary retention. If an enlarged prostate is very severe, a man may not be able to urinate at all. This is known medically as acute urinary retention and usually requires catheterization (inserting a small tube through the penis into the bladder in order to empty the urine). Of the men who took finasteride, 2.8 percent had acute urinary retention that required catheterization, compared to 6.6 percent of men who did not take finasteride.
 
Surgery
In this study, 4.6 percent of men who took finasteride needed to have BPH surgery, while 10.1 percent of men who did not take finasteride needed to have surgery.
 
Urine Flow
Men who took finasteride had an improvement in the rate of urine flow. This increased flow rate was seen as early as the fourth month after starting finasteride and continued throughout the entire study.
 
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About Finasteride

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