Ifex and Breastfeeding

Because Ifex (ifosfamide) does pass through breast milk and can cause serious side effects, the manufacturer recommends women not breastfeed during treatment. Although this medicine is approved for treating testicular cancer in men, it may be used off-label to treat certain cancers in women. Before nursing while using Ifex, talk to your healthcare provider.

Can Breastfeeding Women Use Ifex?

Ifex® (ifosfamide) is a prescription medication used in the treatment of testicular cancer. It belongs to a group of medicines known as alkylating agents. Ifex passes through breast milk. The manufacturer recommends women not breastfeed during treatment.

More Information on Ifex and Breastfeeding

Ifex has been shown to pass through breast milk in humans. The medication is associated with serious side effects, such as low blood cell counts, kidney and bladder damage, and central nervous system toxicity. It has also been reported to cause other cancers and tumors. Because the risk for these effects in a nursing infant cannot be ruled out, it is generally recommended that women receiving Ifex avoid breastfeeding.
At this time, Ifex is only approved for the treatment of cancer of the testicles, which only occurs in men. However, the drug may be used off-label to treat other types of cancer and, therefore, may be used in a woman.

Talking With Your Healthcare Provider

You should discuss breastfeeding and Ifex use with your healthcare provider. Each woman's situation is different, and you and your healthcare provider understand your situation best. After considering what you want and expect, as well as your current health situation, the two of you can make a shared decision that is right for you.
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