Impotence Medication

Other Oral Drugs for Impotence
Oral testosterone can reduce impotence in some men with low levels of natural testosterone, but it is often an ineffective medication and may cause liver damage.
Some people also have claimed that other oral drugs -- including yohimbine hydrochloride, dopamine and serotonin agonists, and trazodone -- are effective at treating impotence, but the results of scientific studies to verify these claims have been inconsistent. The improvements seen after using these drugs may be examples of the placebo effect -- that is, a change that results simply because the patient believes that an improvement will occur.

Injectable Medicines for Impotence

Many men achieve stronger erections by injecting medication into the penis, causing it to become engorged with blood. These injectable drugs widen blood vessels.
Some types include:
  • Papaverine hydrochloride
  • Phentolamine
  • Alprostadil (marketed as Caverject®).
While effective for many men, these drugs may also create unwanted side effects, including persistent erection (known as priapism) and scarring.
Nitroglycerin, a muscle relaxant, can sometimes enhance an erection when rubbed on the penis.


Another way of using alprostadil for impotence is through a system known as MUSE®. This system is used to insert a pellet of alprostadil into the urethra. MUSE uses a prefilled applicator to deliver the pellet about an inch deep into the urethra. With this type of medication for impotence, an erection will begin within 8 to 10 minutes and may last 30 to 60 minutes.
The most common side effects are:
  • Aching in the penis, testicles, and area between the penis and rectum
  • Warmth or burning sensation in the urethra
  • Redness from increased blood flow to the penis
  • Minor urethral bleeding or spotting.
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