Causes of Low Testosterone

Secondary Low Testosterone Causes

Problems with the pituitary gland (in the brainstem) or hypothalamus (in the brain) can cause secondary low testosterone. Some of the possible causes of this condition include:
 
  • A variety of different genetic conditions, such as Kallmann's syndrome
  • High levels of the hormone prolactin (hyperprolactinemia)
  • Various medications, such as corticosteroids (such as prednisone), opioids (for pain), or hormone medications (including testosterone)
  • Diabetes
  • Other chronic illnesses
  • Infection or injury in the brain or brainstem
  • Brain or brainstem tumors
  • Damage to the pituitary gland from radiation therapy.
 

What Is Causing My Low Testosterone?

Your healthcare provider will be able to distinguish between primary and secondary hypogonadism based on the results of blood tests and, in some cases, your symptoms. After that, he or she will try to determine the precise cause. Although some causes are obvious, others may require extensive testing to make a diagnosis. There may also be times when a healthcare provider is unable to determine a specific cause. These are known as "idiopathic" cases.
 
While it is important to try to find the cause of low testosterone and fix it, there are times when a cause cannot be found or fixed. Regardless of the cause, most cases of low testosterone can be treated successfully with testosterone replacement therapy (testosterone medications).
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Low Testosterone Information

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