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Drug Interactions

Doxazosin XL may react with a number of other medicines (see Drug Interactions With Doxazosin XL).

What If I Overdose on This Medication?

An overdose is likely to cause dangerously low blood pressure (hypotension). If you happen to take too much of this medication, seek immediate medical attention.
(Click Cardura XL Overdose for more information.)

What Should I Do If I Forget a Dose of Doxazosin XL?

If you do not take your dose as scheduled, simply skip the missed one and take your next dose instead. Do not take a double dose.

How Does This Medication Work?

Doxazosin XL belongs to a class of drugs known as alpha blockers. There are a few different kinds of alpha receptors in the body, and this medication works mostly at alpha-1 receptors. Alpha-1 receptors are found in several places of the body, including the prostate gland.
When used for the treatment of BPH, alpha-1 blockers help to relax the muscles of the prostate and the bladder neck (where urine leaves the bladder). Doxazosin XL does not shrink the prostate, as some other BPH medications do. However, by relaxing the muscles of the prostate and bladder, it helps to quickly relieve BPH symptoms. Although this medication can treat the symptoms, it is not a cure for BPH.

Clinical Effects of Doxazosin XL

Doxazosin XL has been thoroughly evaluated in clinical studies. These studies showed that doxazosin XL decreased BPH symptoms, such as nighttime urination, frequent urination, and a weak stream, and increased urine flow rate more than a placebo (a "sugar pill" that does not contain any active ingredients) and about as well as immediate-release doxazosin (regular doxazosin).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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