What Should I Do If I Forget a Dose of Doxazosin XL?
If you do not take your dose as scheduled, simply skip the missed one and take your next dose instead. Do not take a double dose.
How Does This Medication Work?
Doxazosin XL belongs to a class of drugs known as alpha blockers. There are a few different kinds of alpha receptors in the body, and this medication works mostly at alpha-1 receptors. Alpha-1 receptors are found in several places of the body, including the prostate gland.
When used for the treatment of BPH, alpha-1 blockers help to relax the muscles of the prostate and the bladder neck (where urine leaves the bladder). Doxazosin XL does not shrink the prostate, as some other BPH medications do. However, by relaxing the muscles of the prostate and bladder, it helps to quickly relieve BPH symptoms. Although this medication can treat the symptoms, it is not a cure for BPH.
Clinical Effects of Doxazosin XL
Doxazosin XL has been thoroughly evaluated in clinical studies. These studies showed that doxazosin XL decreased BPH symptoms, such as nighttime urination, frequent urination, and a weak stream, and increased urine flow rate more than a placebo (a "sugar pill" that does not contain any active ingredients) and about as well as immediate-release doxazosin (regular doxazosin).
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Cardura XL [package insert]. New York, NY: Pfizer, Inc.;2009 July.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed February 4, 2011.
National Library of Medicine (US). Drugs and Lactation Database (LactMED). NLM Web site. Available at: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT. Accessed February 4, 2011.
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