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Before you start treatment with Fortesta, it's important to know that many medications may react with this testosterone gel, including warfarin, insulin, and prednisone. Drug interactions with Fortesta can increase your risk of problems like fluid retention, low blood sugar, and dangerous bleeding. To help limit your risk of problems, make sure your doctor has a complete list of all the medicines you are taking.

An Overview of Interactions With Fortesta

Fortesta™ (testosterone gel) can potentially react with a number of other medications. Some of the drugs that may lead to Fortesta interactions include:
  • Insulin
  • Corticosteroids, such as:
    • Betamethasone (Celestone®)
    • Cortisone
    • Dexamethasone (Decadron®)
    • Fludrocortisone (Florinef®)
    • Hydrocortisone (Cortef®)
    • Methylprednisolone (Depo-Medrol®, Medrol®)
    • Prednisolone (Orapred®, Pediapred®)
    • Prednisone
    • Triamcinolone (Kenalog®, Aristospan®)

Fortesta Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Fortesta is combined with any of the drugs listed above.
Fortesta can decrease blood sugar. If you take insulin, you should monitor your blood sugar more closely when starting or stopping Fortesta, or even when adjusting your dose. You may need to adjust your insulin dosage as well. Check with your healthcare provider for more specific instructions for your particular situation.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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