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The individual dose of Ifex is based on height, weight, and how the medication is tolerated, among other factors. This chemotherapy medicine is given as an IV infusion by a healthcare provider. It is usually given once a day for five days every three weeks. If your blood cell counts remain low, you may have to take a longer break from the drug.
An Introduction to Dosing With IfexThe dose of Ifex® (ifosfamide) your healthcare provider recommends will vary, depending on a number of factors, including:
- Your height and weight
- How you tolerate the medication
- Other medical conditions you may have.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
What Is the Recommended Ifex Dosage?Like many chemotherapy medicines, the Ifex dose your healthcare provider recommends will be based on your body surface area. Body surface area is calculated using your height and weight. Doses based on body surface area are expressed as milligrams (mg) or grams (g) per meter squared (m2).
The usual recommended dose of Ifex for treating testicular cancer is 1.2 g per m2 once a day for five days in a row. This amount is repeated every three weeks. The break in treatment allows your blood cell counts to recover, as Ifex can cause bone marrow suppression (when the bone marrow does not make adequate amounts of blood cells). If your blood cell counts are too low when it is time for your next dose, your healthcare provider may recommend a longer break.
People with liver disease and kidney disease may need lower dosages. Your healthcare provider will consider your liver and kidney function when recommending your specific amount.
Ifex can be toxic to the bladder, and may cause hemorrhagic cystitis, a condition associated with bladder irritation and blood in the urine. In order to reduce the risk for this condition, Ifex is given in combination with a medication known as mesna (Mesnex®). Mesna can be given as an intravenous (IV) injection or as a tablet.