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Nausea, vomiting, and hair loss were some of the most commonly reported side effects when Ifex was given to people during clinical trials. Research also showed that this chemotherapy medication can cause potentially dangerous reactions. Notify your healthcare provider immediately if you develop serious complications, such as blood in the urine, difficulty breathing, or hallucinations, as these may require medical treatment.

An Introduction to Ifex Side Effects

As with any chemotherapy medicine, Ifex® (ifosfamide) can cause side effects. In fact, most people will experience some type of reaction to this drug, and some side effects can be quite significant. Talk to your healthcare provider about ways to prevent or lessen reactions to this medicine.
(This article covers many, but not all, of the possible side effects with Ifex. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects With Ifex

Ifex has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people who received the drug were carefully documented. As a result, it was possible to see what side effects occurred and how often they appeared.
In these studies, the most commonly reported Ifex side effects included:
  • Hair loss -- in up to 89.6 percent of people (see Chemotherapy and Hair Loss)
  • Nausea and vomiting -- up to 46.8 percent
  • Blood in the urine -- up to 44.1 percent
  • A decrease in white blood cell counts -- up to 43.5 percent (see Chemotherapy and Infections)
  • Anemia (low red blood cell counts) -- up to 37.9 percent (see Chemotherapy and Anemia)
  • Problems affecting the central nervous system, such as confusion, changes in mood, and changes in behavior -- up to 15.4 percent
  • Infections -- up to 9.9 percent.
Other common reactions, occurring in 0.08 percent to 4.8 percent of people, included:
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Last reviewed by: Kristi Monson, PharmD;
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