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If you are taking methyltestosterone with insulin, a corticosteroid, or certain other drugs, it may cause dangerous interactions. Some of these negative reactions may increase your risk for fluid retention, liver damage, bleeding, or other serious complications. Tell your healthcare provider about any other medications, vitamins, or supplements you are taking before starting treatment with methyltestosterone.

An Overview of Methyltestosterone Interactions

Methyltestosterone (Methitest®, Testred®) may react with several other medications. Some of the drugs that may interact with methyltestosterone include but are not limited to:
  • Insulin of any kind
  • Corticosteroids, such as:
    • Betamethasone (Celestone®)
    • Cortisone
    • Dexamethasone (Decadron®)
    • Fludrocortisone (Florinef®)
    • Hydrocortisone (Cortef®)
    • Methylprednisolone (Depo-Medrol®, Medrol®)
    • Prednisolone (Orapred®, Pediapred®)
    • Prednisone
    • Triamcinolone (Kenalog®, Aristospan®)

More Detail on Drug Interactions With Methyltestosterone

The following sections explain in detail the potentially negative reactions that can occur when methyltestosterone is combined with any of the drugs listed above.
Methyltestosterone can decrease blood sugar levels. If you take insulin, you should monitor your blood sugar more levels more closely when starting or stopping methyltestosterone, or even when adjusting your dose. You may need to adjust your insulin dosage. Check with your healthcare provider for more specific instructions in your particular situation.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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