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Striant is licensed to increase the body's levels of testosterone in men. The drug is unique, in that it can treat low testosterone due to problems in either the testes or the brain. Occasionally, a healthcare provider may prescribe this medication for an "off-label" use. For example, Striant is occasionally prescribed for women or adolescents with low testosterone levels.

What Is Striant Used For?

Striant™ (testosterone buccal tablet) is a prescription testosterone replacement medication. It is approved for treating certain causes of low testosterone in men. The medicine comes in the form of a special tablet that is applied to the gums twice a day.
There are several different causes of low testosterone in men. Testosterone is produced when the testes are stimulated by certain hormone signals from glands in the brain. Low testosterone can occur if the testes are damaged, absent, or otherwise incapable of producing enough testosterone or if the brainstem cannot produce enough hormone signals to stimulate testosterone production in the testicles.
Although sometimes there is a clear, identifiable cause, such as chemotherapy damage or surgical removal of the testicles, sometimes there is no clear reason for the low testosterone.
Striant can treat either type of low testosterone -- whether the problem lies in the testes or the brain -- because it does not rely on either the testes or the brain to increase testosterone levels.
Common symptoms of low testosterone include:
  • Low sex drive (libido)
  • Problems with erectile function
  • Decreased bone strength
  • Fatigue and low energy
  • Decreased muscle mass and increased fat mass
  • Depression.
Of course, a man could have all these symptoms and still have normal testosterone levels, since most of these symptoms are relatively common. The only real way to diagnose low testosterone is by actually measuring testosterone levels in the blood.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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