Megestrol Side Effects

It is possible to develop side effects while using megestrol. Clinical studies on this drug showed that weakness, insomnia, and vomiting were common reactions. While these types of problems are generally minor, serious complications can also occur. Seek medical treatment right away if you experience things like changes in vision or speech, persistent vomiting, or seizures.

An Introduction to Side Effects of Megestrol

Just like any medicine, megestrol acetate (Megace®) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with megestrol. Your healthcare provider can discuss a more complete list with you.)

Serious Megestrol Side Effects

Some side effects of megestrol are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
    • Vision or speech changes
    • Weakness or numbness in an arm or leg
    • A severe headache
  • Pain, redness, or swelling of one or both arms or legs
  • Signs of a blood clot in the lung, such as:
    • Shortness of breath
    • Sudden chest pain
    • Coughing up blood
  • High blood sugar levels
  • Dizziness, weakness, or extreme tiredness
  • Frequent urination
  • Feeling thirstier than usual
  • Persistent nausea or vomiting
  • An irregular or forcefully beating heart
  • Changes in mood, such as depression
  • Weight gain in the midsection or upper back, or rounding of the face
  • Signs of infection, such as:
  • Seizure
  • Signs of an allergic reaction, such as:
    • A rash or hives
    • Itching
    • Unusual swelling, especially of the mouth or throat
    • Wheezing
    • Difficulty breathing.
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Megestrol Acetate Drug Information

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