Methyltestosterone Side Effects

As an older medication, methyltestosterone has only vague information available about its potential side effects. However, based on the adverse reactions of other androgens, methyltestosterone may cause headaches, acne, and changes in sex drive. There are also some potentially serious side effects that may require medical attention, such as sleep apnea, vomiting, or hostility.

An Introduction to Methyltestosterone Side Effects

Just like any medicine, methyltestosterone (Methitest®, Testred®) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with methyltestosterone. Your healthcare provider can discuss a more complete list with you.)

Side Effects of Methyltestosterone to Report

Some side effects of methyltestosterone are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Any development of male characteristics in women, such as:
    • A deepening voice
    • Enlargement of the clitoris
    • Acne
    • Body or facial hair growth
    • Menstrual changes
    • Rapid weight gain
    • Shortness of breath
    • Fluid retention
  • Infertility
  • Signs of liver damage, such as yellowing of the skin or whites of the eyes (jaundice)
  • Increased bruising or bleeding
  • Symptoms of high blood calcium levels (hypercalcemia), such as:
    • Constipation, nausea, or vomiting
    • Muscle achiness or weakness
    • Kidney stones
    • Abdominal (stomach) pain or side pain
    • Confusion or lethargy
    • Increased thirst and frequent urination
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.
It is important that women taking methyltestosterone report any signs of virilization (development of male characteristics) to their healthcare providers right away. If the drug is stopped quickly, the virilization may be at least partially reversible. However, if methyltestosterone is stopped later, the virilization may be permanent. You and your healthcare provider may decide that you should keep taking methyltestosterone, despite virilization, if the benefits to you are significant.
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Methyltestosterone Drug Information

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