No strong evidence shows that any treatment for Peyronie's disease other than surgery is effective. Experts usually recommend surgery only in long-term cases in which the Peyronie's disease is stabilized and the deformity prevents intercourse.
Because the course of Peyronie's disease is different in each man, and because some patients improve without utilizing any of the treatment options currently available, medical experts suggest waiting one to two years or longer before attempting to correct it surgically.