Drug Interactions With Sildenafil Citrate

Some of the drugs that can potentially interact with sildenafil citrate include cimetidine, ritonavir, and alpha blockers. Drug interactions with sildenafil citrate can cause changes in blood pressure and also cause your body to metabolize the medicines differently than intended. Be sure to talk with your healthcare provider about any sildenafil citrate drug interactions that may apply to you.

Sildenafil

An Introduction to Drug Interactions With Sildenafil Citrate

A number of other medicines can potentially interact with sildenafil citrate (Viagra^®). Some possible drug interactions with sildenafil citrate can include:

Cimetidine (Tagamet^®)
Ritonavir (Norvir^®) and other protease inhibitors
Amlodipine (Norvasc^®, Caduet^®, Lotrel^®)
Alpha blockers for high blood pressure (HBP) or benign prostatic hyperplasia (BPH), such as doxazosin (Cardura^®), prazosin (Minipress^®), and terazosin (Hytrin^®)
Erythromycin
Saquinavir (Fortovase^®)
Antifungals, such as ketoconazole (Nizoral^®), fluconazole (Diflucan^®), or itraconazole (Sporanox^®)
Nitrates, with nitroglycerin being the most common type.

Interactions With Sildenafil Citrate Explained

The following sections explain in detail the potentially negative interactions that can occur when sildenafil is combined with any of the drugs listed above.

Cimetidine

In previous research studies, when cimetidine and sildenafil citrate were given at the same time, the levels of Viagra in the blood increased significantly. To avoid this possible sildenafil citrate drug interaction, it is recommended that you discuss alternatives with your healthcare provider prior to taking sildenafil citrate.

(Drug Interactions With Sildenafil Citrate Continued: Page 2)