Drug Interactions With Silodosin

Silodosin Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when silodosin is combined with any of the drugs listed above.
 
Blood Pressure Medications
Check with your healthcare provider before combining silodosin with a high blood pressure medication, as the combination of these medications may cause dangerously low blood pressure (hypotension).
 
Certain Antibiotics or Antifungals
Some antibiotics and antifungal medications may greatly increase the level of silodosin in your blood, increasing your risk of silodosin side effects. Check with your healthcare provider before taking any antibiotic or antifungal with silodosin. In general, you should not combine silodosin with such antibiotics or antifungals.
 
Certain HIV or AIDS Medications
Some HIV/AIDS medications may greatly increase the level of silodosin in your blood, increasing your risk of Silodosin side effects. Check with your healthcare provider before taking any HIV or AIDS medication with silodosin. In general, you should not combine silodosin with such medications.
 
Erectile Dysfunction Medications
Other medications that are very similar to silodosin can interact with medications for erectile dysfunction (also known as ED or impotence), increasing the risk of dangerously low blood pressure. Although research suggests that silodosin does not seem to interact with these medications, caution should be taken when combining these medications.
 
Imatinib (Gleevec)
Imatinib may greatly increase the level of silodosin in your blood, increasing your risk of silodosin side effects. Check with your healthcare provider before taking imatinib with silodosin. In general, you should not combine silodosin with imatinib.
(Drug Interactions With Silodosin Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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