Drug Interactions With Tadalafil

Tadalafil Interactions Explained

The following sections explain in detail the following interactions that can occur when tadalafil is combined with any of the drugs listed above.
Taking tadalafil with a significant amount of alcohol can cause a fast heart rate (tachycardia), low blood pressure (hypotension), dizziness, and headache.
CYP 3A4 Inhibitors
Tadalafil is broken down ("metabolized") by certain enzymes in the liver known as CYP 3A4 enzymes. Certain other medications (known as CYP 3A4 inhibitors) decrease the activity of the enzymes, thereby increasing the level of tadalafil in the blood. This may lead to serious side effects in some cases. Check with your healthcare provider before combining these medications.
Alpha Blockers
Combing tadalafil with an alpha blocker can cause low pressure, including dangerously low blood pressure in some cases. Check with your healthcare provider before taking these drugs together.
Blood Pressure Medications
Taking tadalafil with a high blood pressure medication may cause your blood pressure to decrease too much. Check with your healthcare provider before combining these drugs.
If you are taking nitrates, you should not use tadalafil. Even if you use a nitrate infrequently, you should not take tadalafil, since you cannot predict when you will need to take the nitrate.
Other Phosphodiesterase Type 5 Inhibitors (PDE5 Inhibitors)
Tadalafil is a PDE5 inhibitor and should not be combined with other such medications, even if they are not used to treat erectile dysfunction.
Taking theophylline and tadalafil together may cause a slight increase in heart rate. Your healthcare provider may choose to make necessary dosing adjustments if you need to take both of these drugs. 
6 Things That Worsen or Cause ED

Tadalafil (Cialis)

Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2020 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.