Drug Interactions With Tadalafil

While taking tadalafil, it is not recommended that you drink large quantities of alcohol. Doing so may cause a decrease in blood pressure, an increase in heart rate, dizziness, or headache.

 

In previous research studies, when alpha blockers and tadalafil were used at the same time for people with benign prostatic hyperplasia (BPH) or high blood pressure, blood pressure decreased. Also, some people experienced lightheadedness, dizziness, or fainting when standing from either a sitting position or lying down. Your doctor may recommend a lower dosage of tadalafil if you are taking an alpha blocker.

 

Taking both tadalafil and ritonavir or indinavir (which are HIV protease inhibitors) may cause your body to metabolize the medications differently than intended. People taking these medicines with tadalafil are more likely to experience a decrease in blood pressure, fainting, or prolonged erection. If you are taking both types of medication, it is important that you take tadalafil no more often than every 72 hours, with a maximum dose of tadalafil 10 mg. Additionally, other HIV protease inhibitors (which have not been studied with tadalafil yet) may cause a similar reaction.

 

Taking both erythromycin and tadalafil may cause your body to metabolize the medicines differently than intended. Your doctor may choose to make necessary dosing adjustments.