Drug Interactions With Tadalafil

Some of the drugs that can potentially interact with tadalafil include nitrates, erythromycin, and high blood pressure medicines. Drug interactions with tadalafil can affect your blood pressure and change how your body metabolizes medicines, among other things. It is important to talk with your healthcare provider about any interactions that may apply to you.

An Introduction to Tadalafil Interactions

Tadalafil (Cialis®) can potentially interact with a number of other medications. Some of the products that may cause tadalafil drug interactions include:
  • Alcohol
  • CYP 3A4 inhibitor medications, such as:






  • Other phosphodiesterase type 5 inhibitors (PDE5 inhibitors), such as:


  • Theophylline (Uniphyl®, Theochron®, TheoCap®, Theo-24®, Elixophyllin®).


(Please note that this article refers specifically to Cialis, the original tadalafil product that is approved for treating erectile dysfunction and enlarged prostate symptoms. For information about the tadalafil product used to treat pulmonary arterial hypertension, please see Adcirca Drug Interactions.) 


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Tadalafil (Cialis)

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