Some of the drugs that can potentially interact with tadalafil include cimetidine, erythromycin, and high blood pressure medicines. Drug interactions with tadalafil can affect your blood pressure and change how your body metabolizes medicines, among other things. It is important to talk with your doctor about any tadalafil drug interactions that may apply to you.
Taking both tadalafil and certain high blood pressure medicines can decrease your blood pressure. Consult your healthcare provider prior to taking tadalafil with any high blood pressure medicine.