Side Effects of Tadalafil (Cont.)

Rare Side Effects of Tadalafil

During clinical studies, there were a number of other side effects that occurred in less than 2 percent of people while they were taking tadalafil. It is difficult to tell whether these side effects occurred because of tadalafil or something else.
 
Some of these possible side effects include but are not limited to:
 
  • Insomnia
  • Unexplained rash
  • Angina
  • Migraines
  • High blood pressure (hypertension)
  • Dry mouth
  • A spinning sensation (vertigo)
  • Blurred vision
  • A sudden decrease in or loss of hearing
  • Other vision problems, such as seeing a blue tinge to objects or difficulty telling the difference between blue and green
  • Prolonged erection lasting longer than four hours
  • Painful erection lasting more than six hours (priapism).
     
In rare cases, serious problems can occur in the heart, brain, or blood vessels. These include:
 
In these cases, most of the people already had cardiovascular risk factors. Also, the side effects occurred during or shortly after sexual activity. For these reasons, it is difficult to tell whether the problems were related to the tadalafil, the person's existing risk factors, sexual activity, or a combination of these things.
 
(Click Precautions and Warnings for Tadalafil for more information.)
 
In people taking PDE5 inhibitors, including tadalafil, there have been rare cases of a condition called non-arteritic anterior ischemic optic neuropathy (NAION). This condition can lead to sudden loss of vision in one or both eyes. If you notice any unexplained changes in your vision while taking tadalafil, report them to your doctor immediately (see Cialis and Blindness).
 
(Side Effects of Tadalafil Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;