When and How Do I Take Tadalafil?

Here are some general considerations regarding when and how to take it:
  • The medication comes in tablet form. It can be taken just as needed, usually one hour before sexual activity (no more than once a day). It can also be taken every day, without regard to timing of sexual activity ("once-daily tadalafil").



  • It is recommended that you take your dose with a glass of water. You may take tadalafil with or without food.


  • For tadalafil to work properly, you have to take it as prescribed. It won't work if you stop taking it.

Side Effects

(The side effects listed below are NOT a complete list of possible side effects of tadalafil. Your healthcare provider can discuss a more complete list of side effects with you.)
There are possible side effects with any medicine, including tadalafil. However, not everyone who takes tadalafil will experience side effects. In fact, most people tolerate it well. When people do develop side effects, in most cases they are minor, meaning they require no treatment or are easily treated by you or your healthcare provider.
The most common side effects of tadalafil include:
  • Headache
  • Indigestion, known as dyspepsia
  • Back pain
  • Facial flushing
  • Nasal congestion
  • Muscle pain (known as myalgia)
  • Pain in the arms or legs.
If you have cardiovascular disease or significant heart disease risk factors, you have an increased chance of serious problems related to your heart, brain, and blood vessels. These problems can lead to dangerous side effects such as heart attack, stroke, or sudden death.
There have also been rare cases of a condition called non-arteritic anterior ischemic optic neuropathy (NAION) in some people taking tadalafil. This condition can lead to sudden loss of vision in one or both eyes. If you experience any loss of vision while taking tadalafil, contact your healthcare provider immediately (see Cialis and Blindness).
(Click Side Effects of Tadalafil to learn more about the specific side effects of this drug.)
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