Testosterone Cypionate Injection Site

When using testosterone cypionate (Depo®-Testosterone), the site of the injection is usually the gluteal muscle. This prescription medicine comes in a special oil formulation, which allows the testosterone to be slowly released from the oil into the bloodstream over a two- to four-week period.
 
Testosterone cypionate must be injected, as taking it by mouth would not effectively increase testosterone levels. When medications are taken orally, they must pass through the liver before they reach the bloodstream. However, the liver significantly metabolizes testosterone before it can reach the bloodstream. Therefore, testosterone cypionate must be injected into a muscle so it can bypass the liver and directly reach the bloodstream.
 
(For more information, click Testosterone Cypionate Dosage. This full-length article takes a closer look at how this injection is administered, how your doctor will determine your dosage, and general tips for using this medicine.)
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