Testosterone Enanthate Side Effects

Possible side effects of testosterone enanthate include inflammation at the injection site, breast development (in men), and headache, among others. However, it is generally well tolerated, and most people are able to undergo treatment without any problems. Notify your healthcare provider immediately if you develop any serious side effects, such as hostility, changes in skin color, or rapid weight gain.

An Introduction to Testosterone Enanthate Side Effects

As with any medicine, side effects are possible with testosterone enanthate (Delatestryl®). However, not everyone who uses the medication will experience problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with testosterone enanthate. Your healthcare provider can discuss a more complete list with you.)

Side Effects of Testosterone Enanthate to Report

Some testosterone enanthate side effects are potentially serious and should be reported to your healthcare provider. These include but are not limited to:
  • Any development of male characteristics in women, such as:
    • Deepening voice
    • Enlargement of the clitoris
    • Acne
    • Body or facial hair growth
    • Menstrual changes
    • Rapid weight gain
    • Shortness of breath
    • Fluid retention
  • Infertility
  • Signs of liver damage, such as yellow eyes or skin (jaundice)
  • Increased bruising or bleeding
  • Symptoms of high blood calcium levels (hypercalcemia), such as:
    • Constipation, nausea, or vomiting
    • Muscle achiness or weakness
    • Kidney stones
    • Abdominal (stomach) pain or side pain
    • Confusion or lethargy
    • Increased thirst and frequent urination
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.
It is important for women using testosterone enanthate to report any signs of virilization (development of male characteristics) to their healthcare providers right away. If the medication is stopped soon, the virilization may be at least partially reversible. However, if testosterone enanthate is stopped later, the virilization may be permanent. You and your healthcare provider may decide for you to keep taking testosterone enanthate, despite virilization, if the benefits to you are significant.
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