Tribulus Terrestris

Tribulus terrestris is a toxic weed that is often used in dietary supplements. These supplements are typically used to enhance sexual function and to improve athletic performance. Tribulus terrestris contains a mixture of different compounds that may be responsible for the medicinal properties of the plant; it may increase the level of various hormones, relax the arteries of the heart, and lower blood pressure.

What Is Tribulus Terrestris?

Tribulus terrestris (also known as puncture vine) is a flowering plant that is usually considered a toxic weed. It has sharp spines that can puncture bicycle tires. This plant is a popular ingredient in dietary supplements, most often used to enhance sexual function or to improve athletic performance.
 
(Click Benefits of Tribulus Terrestris for more information on what the supplement is used for.)
 

How Does It Work?

T. terrestris contains a mixture of different compounds that may be responsible for the medicinal properties of the plant. The root, stem, and fruit contain these compounds. Early research suggests that the plant may increase the level of various hormones (including testosterone and dehydroepiandrosterone, or DHEA) in rats. Although studies have not shown similar effects in humans, people use the supplement for sexual problems and for bodybuilding based on the assumption that it increases hormone levels.
 
T. terrestris may help relax the arteries of the heart. It also may lower blood pressure by inhibiting angiotensin-converting enzymes (much like ACE inhibitor medications). Research also suggests that the plant might have a diuretic effect (it may increase urine production), which may be why some people use it for various kidney problems.
 

Is Tribulus Terrestris Effective?

In general, there is not enough scientific evidence to suggest that T. terrestris really is effective for most uses (see Does Tribulus Terrestris Work? for more information).
 

Dosing Information

There is no established standard dose for T. terrestris, although general dosing guidelines may be obtained from a few clinical studies that evaluated certain uses of the supplement (see Tribulus Terrestris Dosage for more information).
 

Side Effects of Tribulus Terrestris

This supplement has not been reported to cause side effects. However, there are several different side effects that might theoretically occur, based on how the supplement works.
 
(Click Tribulus Terrestris Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 

Drug Interactions

Theoretically, T. terrestris may interact with a few medications (see Tribulus Terrestris Drug Interactions).
 

Safety Issues With Tribulus Terrestris

Short-term use of T. terrestris appears to be relatively safe in many circumstances. However, some people may be more likely to experience problems than others. Therefore, you should talk with your healthcare provider prior to taking the supplement if you have:
 
Also, let your healthcare provider know if you are:
 
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
(Click Is Tribulus Terrestris Safe? for more information, including any available warnings and precautions.)
 

What If I Take an Overdose?

It is not known exactly what to expect from an overdose of this supplement. If you think you or someone else may have taken too much T. terrestris, it is important to seek immediate medical attention.
 
(Click Tribulus Terrestris Overdose for more information.)
 

Storage Methods for Tribulus Terrestris

Refer to the label of your individual product for information on how to best store T. terrestris supplements. Keep all medications and supplements out of the reach of children.
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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